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It also increases microbial diversity in the gut, according to animal studies.[ref] Xanthine oxidoreductase is the enzyme needed for purine metabolism, which results in the formation of uric acid

10.1038/s41598-021-85427-8 25

In this case, the minced cortex was washed with Ca2+/Mg2+-free HBSS containing 25 mM HEPES and 2 mM glycine

The system was heated to a final temperature of 300 K in three steps: 0 to 100 K for 10 ps (NVT), 100 to 200 K for 20 ps, and 200 to 300 K for another 20 ps, all under NPT conditions (1 atm pressure)