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Regulating Satiety Pathways: In the hypothalamus, GLP-1 RAs stimulate neurons that promote satiety (POMC/CART neurons) and inhibit neurons that drive hunger (NPY/AgRP neurons), reducing food intake and enhancing fullness (Zheng et al., 2024)

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Studies conducted on animal subjects specifically looked at the following areas of the GI tract: Intestines Liver Stomach Esophagus Duodenum The findings from this study only further proved to support the original findings of past research