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But because obesity drives many of the major diseases of aging, including heart disease, cancer, dementia, arthritis and diabetes, the US Centers for Medicare and Medicaid Services says it makes sense to pilot a test to see whether the medications might ultimately save the program money and improve health outcomes

Conversely, the remaining 24% are eating more snacks, meats, and other items

These agents block the activin type II receptors (ActRIIA and ActRIIB), which are key mediators of muscle catabolism through the myostatin and activin A signaling pathways

Several promising innovations are on the horizon, aimed at improving patient convenience, enhancing efficacy, reducing side effects, and tailoring therapy to individual needs