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Activated platelets undergo spreading and degranulation, releasing factors including ADP, 5-hydroxytryptamine (5-HT), thrombin, and TXA 2 , which activates platelets by interacting with specific receptors and triggering downstream signaling like the GPIIb/IIIa activation, activating more stable and irreversible platelet aggregation and clot contraction, promoting hemostasis

These findings suggest that GLP1RAs may possess direct neuroprotective functions in the retina independent of their hypoglycaemic effects

GLP-1, dulaglutide, injection Trulicity mimics a gut hormone called glucagon-like peptide-1 (GLP-1)