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Concurrent lifestyle interventionsregular exercise, sleep optimization, stress management, and adequate hydrationdirectly reduce anxiety and improve GLP-1 tolerability

Female participants at the 12mg dose achieved average weight loss of 25.3%, compared to 22.8% for male participants

Furthermore, GLP-1 RAs exhibit anti-inflammatory effects, lowering circulating levels of pro-inflammatory cytokines such as tumor necrosis factor-alpha (TNF-), interleukin-1 beta (IL-1), and IL-6, while promoting anti-inflammatory mediator production [26]

RMSF reads the fluctuation in protein residue in protein-ligand complex and also helps to understand the region in protein with different degrees of fluctuation are impacted by ligand binding