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On average, their patients taking a GLP-1 drug lost 15 pounds (6.8 kg) within 6 to 12 months, and nearly 30 pounds after more than a year

One concern is tolerance

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The clinical features of a typical lipoma A typical lipoma has these characteristics: Soft and doughy gives way easily under finger pressure Mobile moves freely under the skin when pressed from different angles Painless most lipomas cause no symptoms at rest Slow-growing typically grows over months or years, not weeks Well-defined has a clear boundary that can be felt under the skin Round or oval shape A lump with these features is very likely to be a lipoma, and clinical examination alone is often enough to make the diagnosis