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Rats pretreated with the traditional liver tonics Andrographis paniculata (100-200 mg/kg/day) and Picrorhiza kurroa (50-100 mg/kg/day) had lower markers of liver damage (ALT, AST, lipid peroxidation) after acetaminophen intoxication (Nagalekshmi 2011
However, one of the consequences of prolonged estrogen suppression is acquired drug resistance
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