tirzepatide renal impairment 🧬 New data from the SUMMIT trial reveals that long-term (Zepbound) may Tirzepatide (Zepbound) showed improved kidney

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Safety Monitoring Recommendations Based on the available clinical trial data, clinicians prescribing orforglipron should: (1) counsel patients about expected GI side effects during dose escalation, (2) follow the recommended dose-titration schedule to minimize GI intolerance, (3) monitor for signs of pancreatitis and discontinue if suspected, (4) assess hepatic and renal function at baseline and periodically, (5) screen for personal or family history of MTC or MEN 2, and (6) review concomitant medications for potential CYP3A-mediated drug interactions

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Once a vial is first punctured, it should generally be used within 28 days unless the pharmacy label or manufacturer instructions state otherwise