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doi: 10.1016/j.pnpbp.2011.03.021 89 KulakA.SteulletP.CabungcalJ

Currently in Phase 2 and Phase 3 clinical trials, retatrutide simultaneously activates GLP-1, GIP, and glucagon receptors, distinguishing it from existing licensed weight-loss medicines such as semaglutide and tirzepatide

Similarly, a higher proportion of patients receiving semaglutide achieved fibrosis improvement with no worsening of MASH (37% vs