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Studies have shown that glucose uptake decreases in advanced CRC, whereas levels of oxidative metabolites such as glutamate and pyruvate increase, indicating a metabolic shift from glycolysis toward a mitochondria-centered hybrid phenotype [6]

In 14 patients with coronary artery disease and good LV function, intravenous GLP-1 infusion improved global and regional wall LV function on dobutamine stress echocardiography compared with control [92]

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