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Factors such as oxidative stress, inflammation, and alterations in lipid metabolism may also contribute to the observed associations between serum iron levels and gallstone risk [35, 36]

To identify mitochondria-related genes highly correlated with innate or adaptive immune cells, the hub mitochondria-related genes were selected by intersecting genes in WGCNA modules and genes identified from the Mitocarta 3.0 database (35)

Thats an orthopedic finding, about a different kind of surgery entirely, but its evidence this timing question is still being studied rather than closed

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