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A consistent pattern emerges: evidence is mostly limited to animal studies human studies, where they exist, are small and short-term there are no high-quality trials reflecting real-world use, including combinations, higher doses or long-term administration

UK Research suggests that senescent cells impair proteasome activity in the heart, leading to the accumulation of damaged proteins and reduced cardiac function

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This early response may reflect the body's immediate utilisation of available B12 for urgent metabolic processes