Garlic organosulfur compounds were shown to exert their immunomodulatory activity via inhibition of the transcription factor NF-B, leading to decreased levels of pro-inflammatory cytokines, such as TNF-, IL-1, IL-6, MCP-1, and IL-12 ( 2+ from proteins in murine EL-4 T-cells, possibly due to S -thioallylation of Zn 2+ coordinating Cys thiolates ( 2+ levels due to inactivation of host proteins by S -thioallylation
Instead, it operates through a cluster of regenerative and cytoprotective pathways
Chan also recommends avoiding other potentially irritating ingredients, such as alpha hydroxy acids, aka AHAs , including glycolic, lactic, and citric varieties
The rats were maintained on a standard diet of rat chow (14.7% Lipids, 33.0% protein, and 52.2% carbohydrates, with an energy content of 2.75 Kcal/g) and provided with water