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The range of uses for the thiazide and thiazide-like diuretics includes hypertension, congestive heart failure, edema, nephrogenic diabetes insipidus, and nephrocalcinosis (renal stones composed of calcium oxalate or calcium phosphate)

Its protein product functions as a molecular chaperone, facilitating membrane protein secretion and proper folding to maintain membrane integrity, cellular homeostasis, and ER stress responses [37, 38]

NLRP3 inflammasome: from a danger signal sensor to a regulatory node of oxidative stress and inflammatory diseases