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For many patients, this can lead to: Loose or sagging skin Hollow cheeks or temples Increased fine lines and wrinkles Crepey skin texture Loss of facial definition Deflated appearance in areas like the breasts or buttocks These changes are not caused by the medication itself as much as they are the result of rapid weight loss

ISSN 1529-8019

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Researchers are studying the precise neurological pathways involved and how sustained amylin receptor activation influences hunger signalling over time