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In general, the dynamic behavior of a metabolic pathway is modeled by the following differential equation.where x is the variable vector representing metabolite concentrations (n 1), S is the stoichiometry matrix (n m), and v is the reaction rate vector (m 1), which is a function of x

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Mediating the flow of Ca 2+ (Liu et al., 2021), the NMDA receptor is a heterotetramer calcium channel, mainly composed of two NR1 subunits and two NR2 subunits (Furukawa et al., 2005)