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Science 336 , 12621267 (2012)

applied a high dimensional approach to analyze associations between GLP-1 treatment and health outcomes in over 1.9 million persons over an average of 3.68 years based on data from the US Department of Veterans Affairs and found, in addition to gastrointestinal and other common symptoms, a significant increase in hypotension, joint pain, kidney stones, and nephrolithiasis [190]

It is of interest that children with Prader-Willi syndrome, which exhibit hyperphagia and obesity have a low level of plasma PP and infusion of PP in those children leads to reduction in food intake (63)

But the population of people who have taken BPC-157 outside research settings has not been followed for the kind of duration that would resolve the question, and Kekic is unambiguous about what that means for her clinical practice