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Hausauer links the heightened sensitivity to an increase in both the expression of androgen receptors in the follicles as well as an uptick in the enzyme that changes testosterone into DHT, which means that even low or declining circulating testosterone can be converted to the more potent DHT within the follicle. Waning estrogen exacerbates the situation

(Romijn et al

GLP-1RAs modulate immune cell signaling and regulate the nuclear factor-kappa B (NF-B) pathway, impacting inflammatory responses, cytokine production, and oxidative stress attenuation

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