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Healy DL, Breheny S, Halliday J, Jaques A, Rushford D, Garrett C, et al

In essence, it functions as a signaling molecule: when introduced into damaged tissue, it appears to activate multiple healing pathways that help the body repair itself more efficiently

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DOI: 10.1111/acel.14083 Circulation Research (2018) Ahajournals.org Reviewed the roles of SIRT1, SIRT3, SIRT4, SIRT6, SIRT7, and NAD+ across cardiovascular ageing, confirming protective roles against dyslipidaemia, obesity, type 2 diabetes, arrhythmia, cardiac fibrosis, hypertrophy, and ischaemia-reperfusion injury