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Enzymatically-synthesized glycogen induces cecal glucagon-like peptide-1 production and suppresses food intake in mice

[11] Tirzepatide is a prescription medication approved by the FDA for the treatment of type 2 diabetes (under the brand name Mounjaro) and chronic weight management in adults with obesity (BMI 30 kg/m) or overweight (BMI 27 kg/m) with at least one weight-related comorbidity (under the brand name Zepbound)

And preclinical models consistently show benefits for Alzheimers-like pathology. In addition, a combination of their anti-inflammatory effects and effects on the vasculature likely explain some of the beneficial effects on dementia reported in observational studies, Holst says

It is not approved for use in children, and its safety and effectiveness in younger patients have not been established