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Previously unreported effects of RSL3, such as degradation of mTOR signaling pathway protein, p70S6K, and reduction of p-NPM1 levels were identified in the present study and warrant further investigation

Mori S, Tomita T, Fujimura K, et al

Their conclusion stated Overall, this study suggests a significantly increased risk of colorectal cancer (CRC) associated with GLP-1 RA use in patients receiving GLP-1 RAs