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There is not a single answer, there is a clinical decision that takes the whole picture into account

Bioinformatics analysis of data sourced from the National Center for Biotechnology Information (NCBI) database revealed that beyond the increased F/B (Firmicutes/Bacteroides) ratio of CKD patients compared to the healthy control, there is an increased abundance of bacteria closely associated with kidney impairment in the CKD group, including Ralstonia and Porphyromonas which are known to correlate negatively with estimated glomerular filtration rate (eGFR) and may serve as markers of CKD progression (Liu W

Clinical implementation thus begins with an assessment of dietary patterns, geographic context, and, when feasible, biochemical status such as plasma selenium or urinary iodine concentration (200, 239)