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8a) and suffers from inhomogeneous cellular distribution 39

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Thus, for a number of them, even if they are good substrates in vitro , other clearance pathways may be more important in vivo or, if they are cleaved by DPP-4, removal of the N-terminal dipeptide may have no effect upon their biological activity

Contudo as altas variaes nos ndices de insulina no sangue, geralmente decorrentes do consumo exagerado de carboidratos, levam ao acmulo de gordura e ao desejo de ingerir ainda mais carboidratos