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Side Effects Change in how much or how often you urinate, lower back or side pain, blood in your urine Unusual moods or behaviors, depression, thoughts of hurting yourself or others Blurred vision or any other change in vision Warnings Tell your doctor if you are breastfeeding, or if you have kidney disease, pancreas problems, diabetes, digestion problems (including gastroparesis), or a history of diabetic retinopathy or depression

Apple flavonol quercetin has been shown to lower systolic blood pressure, improve endothelial function, and lessen the risk of cardiovascular disease (585587)

Nat Immunol (2011) 12(3):22230

Fecal microbiota transplantation reverses insulin resistance in type 2 diabetes: a randomized, controlled, prospective study