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Upon activation, TGF-1 plays a critical role in the ECM remodelling process and fibrogenesis, regulating the expression of MMPs and TIMPs and the deposition of critical ECM components

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Efficacy and safety of once-weekly semaglutide versus once-daily insulin glargine as add-on to metformin (with or without sulfonylureas) in insulin-nave patients with type 2 diabetes (SUSTAIN 4): a randomized, open-label, parallel-group, multicentre, multinational, phase 3a trial

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