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Graphical abstract Similar content being viewed by others Introduction Diabetic neuropathy (DN) is one of the most common and disabling complications of diabetes mellitus worldwide, and its painful form, painful diabetic peripheral neuropathy (PDPN), further degrades patient outcomes [1]

Surgical removal of the thyroid is sometimes performed to treat conditions such as hyperthyroidism, thyroid cancer, or a goiter producing excess hormone

Xenobiotic and endogenous compounds detoxification Glutathione is involved in detoxification via its redox-active sulfhydryl group (-SH)

Because they hit different targets and the combination is stronger