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Notably, in the cerebellum, the D-Cys pathway predominates and produces more H 2 S and protects cerebellar neurons from oxidative stress more effectively than the L-Cys pathway

At subtoxic concentrations, H 2 S has been shown to stimulate ATP production at the level of oxidative phosphorylation, both as a source of electron equivalents for the mETC (via SQR-mediated quinone reduction, Table 1), and through per-sulphidation of ATPase, which maintains the enzyme in its activated state

Think of it like pouring a carbonated beverage down the side of a glass to avoid excess foam

Cav-1 has also been proved to modulate vascular tone in animal models