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Unlimited water is recommended

While the obvious health risk to the athlete here is ending up dead, carbon-monoxide inhalation or rebreathing, as they prefer to say in cycling has been in use for many years, a well-worn technique applied across endurance sport to measure total haemoglobin mass and blood volume, particularly when it comes to the effectiveness of altitude training

The association becomes stronger at higher levels, with severe hyperhomocysteinaemia (above about 30 mol/L) showing a clearer relationship with clotting risk than mild elevations in the 15-30 mol/L range (5)

The post argues the risk-benefit profile favors optimizing or switching a single agent instead of stacking two