Educating the patient about insulin pump operation, insertion site care, troubleshooting techniques, blood glucose monitoring, and calculating insulin doses based on carbohydrate counting promotes effective self-management
It can turn on GLP-1, GIP, and glucagon receptors all at once
Drug working concentrations and stock preparation were as follows: GLP-1MK-801 and MK-801 (both 50 M, dissolved in aCSF or magnesium-free aCSF), NMDA (100 M, dissolved in magnesium free aCSF), CNQX (10 M, dissolved in DMSO, Alomone Labs), picrotoxin (100 M, dissolved in DMSO)
When released after eating, GLP-1 signals the pancreas to produce insulin, reduces the release of glucagon, slows stomach emptying, and communicates with the brain to increase feelings of fullness