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For a drug with $1 billion in annual sales, the difference between a solo exclusivity and one contested by an AG can represent $75 million to $150 million in foregone revenue for the first filer

If side effects are severe, discuss with your healthcare provider whether a slower dose escalation schedule might improve tolerability

Biosimilar developers must demonstrate comparability across multiple dimensions, including primary sequence, higher-order structure, aggregation, impurity profiles, and biological activity