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In those models, disturbed iodine availability impairs the synthesis of thyroid hormones, resulting in compensatory enlargement of the thyroid

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However, juniper berry extract has not yet entered the clinical research stage, and its safety, efficacy and mechanism of action still need to be further verified by systematic preclinical studies and clinical trials

Although it remains unclear whether the glycogen accumulation reflects increased glucose uptake or reduced oxidation, these findings suggest a shift in hepatic carbohydrate flux toward storage and anabolic processing, potentially reflecting enhanced hepatic insulin sensitivity in the absence of GPR146