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Following completion of the second test session, the 45 subjects were randomly assigned to receive 1.5 g, 3.0 g, or 4.5 g GPLC per day for a 28 day period

Methods and compositions for oral administration of protein and peptide therapeutic agents

Although GLP-1 and GIP share an insulinotropic effect and promote expansion of beta-cell mass, they have contrary effects on postprandial glucagon secretionthe former suppresses glucagon response and the latter enhances it during hypoglycaemic or euglycaemic states [23, 56]

Knechtle, B