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Clinical research demonstrated that AOD-9604 had no effect on serum IGF-1 levels, confirming that the peptide fragment does not activate the traditional growth hormone receptor pathway

NCI-EGSSO-SSO-ESSO 2021

A patient should ask a provider before taking berberine if they use: Transplant medicine Multiple daily prescriptions Other supplements that affect blood sugar This step matters because supplement interactions can happen quietly

This specificity comes from growth hormone direct lipolytic action on visceral adipocytes, which express higher concentrations of growth hormone receptors than subcutaneous fat cells