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AH - + Fe 3+ - - - A - + Fe 2+ + H + AH - + Cu 2+ - - - A - + Cu + + H + H 2 O 2 + Fe 2+ - - - HO + Fe 3+ + - OH H 2 O 2 + Cu + - - - HO + Cu 2+ + - OH LOOH + Fe 2+ - - - LO + Fe 3+ + - OH LOOH + Cu + - - - LO + Cu + + - OH HO , LO - - - Lipid peroxidation Adapted from Carr and Frei [15] These radical species are highly reactive and can trigger lipid peroxidation reactions

Choung, R

Molecular Metabolism , 46 , 101131

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