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Treating aged C57BL/6 mouse pancreatic islets with MOTS-c reduced pancreatic islet senescence by modulating nuclear gene expression and metabolites involved in -cell senescence

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Oncogenes and pro-oncogenic genes are poorly studied in CR and carcinogenesis contexts Searching in PubMed revealed only 32.2% (39/121) of our CR cancer-associated genes (Supplementary Data 7) are associated with terms caloric or calorie or caloric restriction or calorie restriction or dietary restriction

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