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In a study of over 17,000 people, semaglutide, a GLP-1 receptor agonist medication, was found to lower the risk of cardiovascular events like heart attacks and strokes by 20% in people who have pre-existing cardiovascular disease and who are overweight, but do not have Type 2 diabetes

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Overexpression of miR-100 suppressed the cell proliferation and cell migration and reduced IGF-1-induced signaling activity by dephosphorylation of p70S6K and 4EB-P1