Topical application through cream or serum can work for localized skin improvements, but absorption is limited, concentrations in commercial products are often insufficient, and youre not getting systemic effects that benefit hair follicles, internal wound healing, or broader tissue remodeling
manufacturers of FDA-approved semaglutide and tirzepatide, and that "they do not sell these medications for compounding." The FDA has published safety concerns specifically about compounded and unapproved GLP-1 products, including reports of adverse events
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They are approved only for type 2 diabetes and weight management within specialist services
