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Elsevier Inc

Uncontrolled levels of oxidative stress may lead to inflammation, accelerate aging and facilitate the development of chronic conditions

When this system is working well, the transition from the resting phase to the growth phase is more efficient

Under oxidative stress, two molecules of GSH react, forming the oxidized GSH disulphide (GSSG) (Figure 2A) [19], which can be reconverted to its reduced form (GSH) by glutathione reductase (GR)