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From a mechanistic point of view, glucose uptake into brown adipose tissue seems to play an important role
To prove the exact underlying baseline neuro-circuitry within the ACC of MIA mice versus C57BL/6J mice would require electrophysiological records from the ACC oxytocin neurons at baseline in the MIA and normal C57BL/6J mice along with any potential changes that may occur with MT-II administration
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11.1 Animal studies Animal and in vivo studies have shown enhanced steroid responsiveness, lower airway hyperresponsiveness (AHR), and reduction in inflammatory cells and oxidative stress in asthma (150153)
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