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It plays a pivotal role in glucose metabolism and appetite regulation through multiple mechanisms: Enhances insulin secretion: GLP-1 stimulates pancreatic -cells to release insulin in a glucose-dependent manner Suppresses glucagon: Reduces hepatic glucose production Delays gastric emptying: Creates prolonged satiety Central nervous system effects: Acts on appetite centers in the brain to reduce hunger and food intake Protects pancreatic -cells: Promotes cell proliferation and inhibits apoptosis GLP-1 Receptor Agonists in Clinical Practice GLP-1 receptor agonists (GLP-1 RAs) are medications designed to mimic the action of endogenous GLP-1 but with enhanced pharmacokinetic properties
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It reduces local inflammation and supports tissue maintenance, but it works best alongside a broader treatment plan that addresses mechanical load
Oladosu PO, Moses N, Adigwe OP, Egharevba HO (2021) Potentials of medicinal plants with antiviral properties: the need for a paradigm shift in developing novel antivirals against COVID-19
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