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The 1998 report found ipamorelin released GH without elevating ACTH or cortisol beyond what GHRH stimulation produced, and later work describes no significant elevation of prolactin, FSH, LH or TSH even at doses reported as more than 200-fold above the GH-releasing ED50

Therefore, DMSO control with 1.3% ( 640 M atpenin) was added to exclude false positive cell toxicity

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In addition to skin-lightening effects, kojic acid also contains some antimicrobial properties