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Bitter orange extract, standardized for synephrine, is a well-known thermogenic agent that stimulates the sympathetic nervous system, promoting increased energy expenditure and fat breakdown

Paul Edison, a professor of neuroscience at Imperial College London who worked with Novo Nordisk on an earlier Alzheimers trial, said the participants in the trials may have been treated too late in their disease

Hong, H., Chen, L., Zhong, Y., Yang, Z., Li, W., Song, C., & Leng, H

This selection is further supported by the CV outcomes data for specific GLP-1RAs, which point to benefits in reducing the risk of MACE in at-risk individuals [16,17,18]