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10.1186/s12967-023-04166-8 155 YangF.YanS.HeY.WangF.SongS.GuoY.et al (2008)

The study showed the validity of quantification of hunger, satiety, and prospective food consumption measured by VAS as well as measurement of ad libitum energy consumption and showed that the appetite recordings during the breakfast meal predicted the energy intake during the lunch meal [3]

Delayed gastric emptying leaves food and liquid in the stomach longer, increasing stretch and chemical stimulus to visceral afferents that communicate with the brainstem nausea centers

The lawsuits against makers of these drugs revolves around the claim that users were not adequately informed about potential health risks associated with their use