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Endothelial cells comprise the inner monolayer of blood vessels that forms a barrier between the artery wall and circulating blood is responsible for regulating vascular tone, regulation of hemostatic properties on the vascular surface, and determining blood-tissue/brain permeability (Paschos and FitzGerald, 2010)

Active ingredients are delivered through the skin into the bloodstream rather than being broken down through digestion, helping reduce nutrient loss and wasted ingredients

Approximately 70% of the structural support provided by the dermis is due to collagen

Some patients report modest weight changes of 1 to 3 pounds, likely related to reduced inflammation-driven fluid retention rather than fat loss