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doi: 10.1093/infdis/jiac136 91 HadjadjJYatimNBarnabeiLCorneauABoussierJSmithNet al

In that work, co-immunoprecipitation analysis showed reduced binding between caveolin-1 and eNOS, an interaction normally responsible for limiting eNOS activity

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393,394 Such observations have generated significant interest in identifying PHD-modifying therapeutics, and a number of PHD inhibitors have been described