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Both excesses and deficiencies of certain nutrients, as well as exposure to heavy metals, toxins, and endocrine disruptors, can disrupt immune tolerance

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The April 2026 FDA action removes them from the Category 2 restricted compounding list effective April 23, 2026, and the FDAs Pharmacy Compounding Advisory Committee will review their compounding eligibility under 503A at its July 23-24, 2026 meeting