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The role of low-grade inflammation in ME/CFS (Myalgic Encephalomyelitis/Chronic fatigue Syndrome) - associations with symptoms

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GSH, the most abundant intracellular nonprotein thiol, plays a key role in intracellular defense, and decreased concentrations of this antioxidant are correlated with the increased frequency of reactive oxygen species (ROS)-mediated mitochondrial damage and apoptosis [9, 10]

This tension is not a reason to avoid GH peptides in patients with insulin resistance but it is a reason why glucose monitoring and clinical oversight are non-negotiable