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3.2 Neurotransmitter-related biomarkers In general, patients with PD have degeneration of dopaminergic neurons in the SN compacta, decreased dopamine levels in striatal areas, and decreased levels of the dopamine metabolites homovanillic acid (HVA) and dihydroxyphenylacetic acid (DOPAC)

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10.1096/fj.202402816RR 203 ZhangP.LeuJ