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In some embodiments, the auris-acceptable penetration enhancer is a surfactant comprising hexyl-, heptyl-, octyl-, nonyl-, decyl-, undecyl-, dodecyl-, tridecyl-, tetradecyl, pentadecyl-, hexadecyl-, heptadecyl-, and octadecyl - or -D-maltoside

Conversely, 24-h Aplnr-CreERT2 induction with 4-hydroxytamoxifen (4-OHT) resulted in widespread GFP expression in E12.5 mesenteric and intestinal vessels, whereas SOX17 + vessels connected to the CMA remained GFP low (Supplementary Fig