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The peptide blend offers a new way to study whether dual-pathway activation changes markers of adiposity, fatty acid oxidation, or body composition

(Utilization in the commercial and Medicaid businesses were as expected.) Lower-than-expected MA reimbursement: Optum Health, United's care delivery division that serves Medicare patients (mostly UHC MA enrollees), grew as patients moved from market-exiting plans to plans (like UHC) that contracted with Optum provider services

PMID: 35658024): The study showed mean weight reduction of 15.0% , 19.5% , 20.9% vs 3.1% placebo at 72 weeks The study showed up to 36% of participants achieved 25% or more weight loss with tirzepatide 15 mg Tirzepatide Once Weekly for the Treatment of Obesity in People with Type 2 Diabetes (SURMOUNT-2) , published in The Lancet (Garvey WT et al., 2023